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Article

DEN1 deneddylates non-cullin proteins in vivo.

Journal of cell science - 1 Oct 2008

Chan Yaru, Yoon Jeongsook, Wu June-Tai, Kim Hyung-Jun, Pan Kuan-Ting, Yim Jeongbin, Chien Cheng-Ting

Abstract excerpt

The ubiquitin-like protein Nedd8/Rub1 covalently modifies and activates cullin ubiquitin ligases. However, the repertoire of Nedd8-modified proteins and the regulation of protein neddylation status are not clear. The cysteine protease DEN1/NEDP1 specifically processes the Nedd8 precursor and has...

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PMID: 18782863
DOI: 10.1242/jcs.030445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18782863-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

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DEN1 deneddylates non-cullin proteins in vivo.PMID 18782863Read ↗

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DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis.Semantic proximity Read ↗

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