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Article

Inositol pyrophosphates as mammalian cell signals.

Science signaling - 23 Aug 2011

Chakraborty Anutosh, Kim Seyun, Snyder Solomon H

Abstract excerpt

Inositol pyrophosphates are highly energetic inositol polyphosphate molecules present in organisms from slime molds and yeast to mammals. Distinct classes of enzymes generate different forms of inositol pyrophosphates. The biosynthesis of these substances principally involves phosphorylation of inositol hexakisphosphate (IP₆) to generate the pyrophosphate IP₇. Initial insights into functions of these substances...

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Identifiers

PMID: 21878680
DOI: 10.1126/scisignal.2001958
PMCID: PMC3667551

Genes

IPMK

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