Article
SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
1 Jan 2011
Abstract excerpt
BACKGROUND: SLUG is a zinc-finger transcription factor of the Snail/Slug zinc-finger family that plays a role in migration and invasion of tumor cells. Mechanisms by which SLUG promotes migration and invasion in prostate cancers remain elusive. METHODS: Expression level of CXCR4 and CXCL12 was examined by Western blot, RT-PCR, and qPCR analyses. Forced expression of SLUG was mediated by retroviruses, and SLUG and...
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