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Article

KLF2 Inhibits the Migration and Invasion of Prostate Cancer Cells by Downregulating MMP2

6 Dec 2018

Abstract excerpt

KLF2, a member of the Kruppel-like factor (KLF) family, is thought to be a tumor suppressor in many kinds of malignant tumors. Its functions in prostate cancer (PCa) are unknown. This study aimed to explore the role of KLF2 in the migration and invasion of PCa cells. The expression of KLF2 was measured by immunohistochemistry in PCa tissues and in paired non-tumor tissues. KLF2 and MMP2 expression in cells was...

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PMID: 30520325
DOI: 10.1177/1557988318816907

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