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Article

MicroRNA-494-3p targets CXCR4 to suppress the proliferation, invasion, and migration of prostate cancer

18 Mar 2014

Abstract excerpt

BACKGROUND: Although SDF-1/CXCR4 pathway is a potential mechanism of tumor proliferation and progression, the mechanism of controlling CXCR4 expression is not fully understood. This study was to confirm that miR-494-3p might be a potentially post-transcriptional regulator of CXCR4 and over-expression of miR-494 might suppress prostate cancer progression and metastasis. MATERIALS AND METHODS: We firstly postulated...

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PMID: 24644030
DOI: 10.1002/pros.22795

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