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Article

Angiogenic sprouting is regulated by endothelial cell expression of Slug (Snai2)

1 Jan 2014

Abstract excerpt

The Snail family of zinc-finger transcription factors are evolutionarily conserved proteins that control processes requiring cell movement. Specifically, they regulate epithelial-to-mesenchymal transitions (EMT) where an epithelial cell severs intercellular junctions, degrades basement membrane and becomes a migratory, mesenchymal-like cell. Interestingly, Slug expression has been observed in angiogenic...

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PMID: 24554431
DOI: 10.1242/jcs.143420

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