Article
Relevance of apolipoprotein E4 for the lipid profile of Brazilian patients with coronary artery disease.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Feb 2007
Souza D R S, Nakachima L, Biagioni R B, Nakazone M A, Pinhel M A S, Trindade D M, Mafra V T, Tácito L H B, Martin J F V, Pinheiro Júnior S, Brandão A C
Abstract excerpt
Apolipoprotein E (apoE - e2, e3, e4 alleles) plays a role in the regulation of lipid metabolism, with the e4 considered to be a risk factor for coronary artery disease (CAD). We aimed to evaluate the apoE polymorphisms in Brazilians with CAD and their influence on the lipid profile and other risk factors (hypertension, diabetes mellitus, smoking). Two hundred individuals were examined: 100 patients with...
Topics
- Adult
- Aged
- Alleles
- Apolipoproteins E
- Case-Control Studies
- Coronary Artery Disease
- Female
- Genotype
- Humans
- Lipids
- Male
- Middle Aged
- Polymorphism, Genetic