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Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease

11 Mar 2024

Abstract excerpt

BACKGROUND AND AIMS: Elderly familial hypercholesterolemia (FH) patients are at high risk of coronary heart disease (CHD) due to high cholesterol burden and late onset of effective cholesterol-lowering therapies. A subset of these individuals remains free from any CHD event, indicating the potential presence of protective factors. Identifying possible cardioprotective gene expression profiles could contribute to...

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PMID: 38663317
DOI: 10.1016/j.atherosclerosis.2024.117507

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