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Article

Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques.

Thrombosis and haemostasis - 1 Jan 2012

Clauser Sylvain, Meilhac Olivier, Bièche Ivan, Raynal Pierre, Bruneval Patrick, Michel Jean-Baptiste, Borgel Delphine

Abstract excerpt

Vitamin K-dependent protein Gas6 (growth-arrest specific gene 6) plays a role in vascular smooth muscle cell (VSMC) survival and migration, as well as in endothelium and leukocyte activation, and could therefore be involved in atherosclerosis. However, the study of mouse models has led to contradictory results regarding the pro- or anti-atherogenic properties of Gas6, and relatively few data are available in...

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Share to Anti-Inflammatory Agents
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Adhesion Molecule-1

Share to Intercellular Signaling Peptides and Proteins

Share to Myocytes, Smooth Muscle

Share to Plaque, Atherosclerotic

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Identifiers

PMID: 22072012
DOI: 10.1160/TH11-05-0368

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TNF

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