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SLC4A10 impedes atherosclerosis by diminishing IFN-γ/GZMB levels of CD8+ T cells via the MAPK pathway

29 May 2025

Abstract excerpt

Background and aims CD8+ T cell subpopulations participate in the formation of atherosclerotic plaques through activation or exhaustion. Yet, it is unclear which specific subset it critically involved. The SLC4A10+ CD8+ T cell possess atherogenic attributes and this study aimed to investigate the associated pathway involved in affecting plaque stability. Methods Carotid plaques were collected from patients that...

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PMID: 40510365
DOI: 10.3389/fimmu.2025.1568999

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