Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The platelet glycoprotein Ia-IIa-associated Br-alloantigen system is expressed by cultured endothelial cells.

British journal of haematology - 1 Aug 1990

Giltay J C, Brinkman H J, Vlekke A, Kiefel V, van Mourik J A, von dem Borne A E

Abstract excerpt

To obtain information on the immunological relationship between the endothelial and platelet glycoprotein (GP)Ia-IIa (VLA-2) complex, we studied whether endothelial GPIa-IIa was able to express the platelet GPIa-IIa-associated Br-alloantigen system. Therefore, we tested antisera to both allelic f...

Topics

Alleles
Antigens, Human Platelet
Blood Platelets
Cells, Cultured
Endothelium, Vascular
Humans
Infant, Newborn
Integrin beta3
Isoantigens
Platelet Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2207007
DOI: 10.1111/j.1365-2141.1990.tb07798.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2207007-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The platelet glycoprotein Ia-IIa-associated Br-alloantigen system is expressed by cultured endothelial cells.PMID 2207007Read ↗

Brb, a platelet alloantigen involved in neonatal alloimmune thrombocytopenia.Semantic proximity Read ↗

Gova/b alloantigen system on human platelets.Semantic proximity Read ↗

Adhesive and signaling properties of a naturally occurring allele of glycoprotein IIIa with an amino acid substitution within the ligand binding domain-the Pena/Penb platelet alloantigenic epitopes.Semantic proximity Read ↗

Localization of the Br polymorphism on a 144 bp exon of the GPIa gene and its application in platelet DNA typing.Semantic proximity Read ↗

The human platelet alloantigens, HPA-5(a+, b-) and HPA-5(a-, b+), are associated with a Glu505/Lys505 polymorphism of glycoprotein Ia (the alpha 2 subunit of VLA-2).Semantic proximity Read ↗

Sra, a private platelet antigen on glycoprotein IIIa associated with neonatal alloimmune thrombocytopenia.Semantic proximity Read ↗

Evidence that platelet-derived microvesicles may transfer platelet-specific immunoreactive antigens to the surface of endothelial cells and CD34+ hematopoietic stem/ progenitor cells--implication for the pathogenesis of immune thrombocytopenias.Semantic proximity Read ↗

Expression and purification of functional recombinant epitopes for the platelet antigens, PlA1 and PlA2.Semantic proximity Read ↗

Max(a), a new low-frequency platelet-specific antigen localized on glycoprotein IIb, is associated with neonatal alloimmune thrombocytopenia.Semantic proximity Read ↗

Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes.Semantic proximity Read ↗

Development of a monoclonal antibody capable of differentiating platelet PLA1/PLA1, PLA1/PLA2 and PLA2/PLA2 genotypes.Semantic proximity Read ↗

Threonine-145/methionine-145 variants of baculovirus produced recombinant ligand binding domain of GPIbalpha express HPA-2 epitopes and show equal binding of von Willebrand factor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.