Article
Max(a), a new low-frequency platelet-specific antigen localized on glycoprotein IIb, is associated with neonatal alloimmune thrombocytopenia.
Blood - 1 Aug 1995
Noris P, Simsek S, de Bruijne-Admiraal L G, Porcelijn L, Huiskes E, van der Vlist G J, van Leeuwen E F, van der Schoot C E, von dem Borne A E
Abstract excerpt
We have identified a new platelet-specific alloantigen, Max(a), responsible for a typical case of neonatal alloimmune thrombocytopenic purpura. The maternal serum reacted strongly with paternal platelets in the platelet immunofluorescence test, whereas platelet alloantigen typing showed that no k...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Blood Platelets
- Female
- Humans
- Infant, Newborn
- Infant, Newborn, Diseases
- Isoantigens
- Male
- Molecular Sequence Data
- Pedigree
- Platelet Membrane Glycoproteins
- Polymorphism, Restriction Fragment Length
- Thrombocytopenia