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Article

Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes.

Blood - 1 Aug 1991

Goldberger A, Kolodziej M, Poncz M, Bennett J S, Newman P J

Abstract excerpt

The subunits that comprise the platelet-specific integrin alpha IIb beta 3 are polymorphic in nature, with several allelic forms present in the human gene pool. Minor changes in the secondary and tertiary structures of platelet membrane glycoproteins (GP) IIb and IIIa encoded by these alleles can result in an alloimmune reaction after transfusion or during pregnancy. To better understand the molecular structure...

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PMID: 1713513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes.PMID 1713513Read ↗

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