Article
Sra, a private platelet antigen on glycoprotein IIIa associated with neonatal alloimmune thrombocytopenia.
Blood - 1 Dec 1990
Kroll H, Kiefel V, Santoso S, Mueller-Eckhardt C
Abstract excerpt
A new platelet alloantigen, Sra, is described that was defined by an alloantibody detected in the serum of a healthy mother who delivered a child with typical clinical signs of neonatal alloimmune thrombocytopenia (NAIT). The antibody reacted strongly with the child's and father's platelets, but not with platelets of the mother or with those of a highly selected panel representing all known platelet alloantigens....
Topics
- Adult
- Antibodies, Monoclonal
- Blood Platelets
- Blotting, Western
- Chymotrypsin
- Female
- Gene Frequency
- Humans
- Immunoassay
- Immunosorbent Techniques
- Infant, Newborn
- Isoantigens