Article
[Association of polymorphism of protein tyrosine phosphatase nonreceptor-22 gene with AITD].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Aug 2008
Yu Zhi-Yun, Zhang Jin-An, Maier Ha-Ba, Wang Yu, Xiao Wan-Xia, Quan Ying, Dong Bao-Ning
Abstract excerpt
AIM: To evaluate the association of PTPN22 gene polymorphism with autoimmune thyroid disease (AITD) in Chinese people and to analyze the relationship between SNP of CTLA-4 gene and SNP of PTPN22 gene. METHODS: 149 patients with Graves' disease (GD) and 82 patients with Hashimoto's thyroiditis (HT) as well as 131 healthy people as controls were investigated. PTPN22 gene polymorphism +1858 C>T and CTLA-4 gene...
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