Association of the protein tyrosine phosphatase nonreceptor 22 haplotypes with autoimmune thyroid disease in the Japanese population.

doi:10.1089/thy.2010.0104

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of the protein tyrosine phosphatase nonreceptor 22 haplotypes with autoimmune thyroid disease in the Japanese population.

Thyroid : official journal of the American Thyroid Association - 1 Aug 2010

Ban Yoshiyuki, Tozaki Teruaki, Taniyama Matsuo, Nakano Yasuko, Ban Yoshihisa, Ban Yoshio, Hirano Tsutomu

Abstract excerpt

BACKGROUND: A missence single-nucleotide polymorphism (SNP) in the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene known as R620W (rs2476601) was recently reported to be associated with several autoimmune diseases including Graves' disease (GD). The association was repeatedly confirmed in the populations of North European ancestry. However, this amino acid was reported to be nonpolymorphic in the Asian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Haplotypes

Share to Interleukin-2 Receptor alpha Subunit

Share to Introns

Share to Japan

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Thyroid Diseases

Source

Open in PubMed

Identifiers

PMID: 20615141
DOI: 10.1089/thy.2010.0104

Genes

PTPN22

Variants

rs2476601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the protein tyrosine phosphatase nonreceptor 22 haplotypes with autoimmune thyroid disease in the Japanese population.PMID 20615141Read ↗

Susceptibility influence of a PTPN22 haplotype with thyroid autoimmunity in Koreans.Semantic proximity Read ↗

The Relationship between PTPN22 R620W Polymorphisms and the Susceptibility to Autoimmune Thyroid Diseases: An Updated Meta-analysis.Semantic proximity Read ↗

Association of PTPN22 haplotypes with type 1 diabetes in the Japanese population.Semantic proximity Read ↗

Associations of protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene polymorphisms with susceptibility to Graves' disease in a Japanese population.Semantic proximity Read ↗

[Association of polymorphism of protein tyrosine phosphatase nonreceptor-22 gene with AITD].Semantic proximity Read ↗

DNA hypermethylation of PTPN22 gene promoter in children and adolescents with Hashimoto thyroiditis.Semantic proximity Read ↗

Association of Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) C1858T gene polymorphism with susceptibility to autoimmune thyroid diseases: a meta-analysis.Semantic proximity Read ↗

The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes.Semantic proximity Read ↗

Multiple SNPs in intron 41 of thyroglobulin gene are associated with autoimmune thyroid disease in the Japanese population.Semantic proximity Read ↗

The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future.Semantic proximity Read ↗

Analysis of chosen polymorphisms rs2476601 a/G - PTPN22, rs1990760 C/T - IFIH1, rs179247 a/G - TSHR in pathogenesis of autoimmune thyroid diseases in children.Semantic proximity Read ↗

Association of single nucleotide polymorphism rs3792876 in SLC22A4 gene with autoimmune thyroid disease in a Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.