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Article

When control fails: influence of the prefrontal but not striatal dopaminergic system on behavioural flexibility in a change detection task.

Neuropharmacology - 1 Feb 2012

Schulz Stefanie, Arning Larissa, Pinnow Marlies, Wascher Edmund, Epplen Jörg T, Beste Christian

Abstract excerpt

There is growing interest in understanding the neurobiological foundations of attention. To examine whether attentional processes in a change detection task are modulated by dopamine signalling, we investigated the influence of two polymorphisms, i.e. Val158Met (rs4680) in the catechol-O-methyl transferase (COMT) and a variable number of tandem repeats polymorphism (VNTR, rs28363170) in the dopamine transporter...

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Source

Identifiers

PMID: 22067551
DOI: 10.1016/j.neuropharm.2011.10.012

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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