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Article

African ancestry protects against Alzheimer's disease-related neuropathology.

Molecular psychiatry - 1 Jan 2013

Schlesinger D, Grinberg L T, Alba J G, Naslavsky M S, Licinio L, Farfel J M, Suemoto C K, de Lucena Ferretti R E, Leite R E P, de Andrade M P, dos Santos A C F, Brentani H, Pasqualucci C A, Nitrini R, Jacob-Filho W, Zatz M

Abstract excerpt

Previous studies in dementia epidemiology have reported higher Alzheimer's disease rates in African-Americans when compared with White Americans. To determine whether genetically determined African ancestry is associated with neuropathological changes commonly associated with dementia, we analyzed a population-based brain bank in the highly admixed city of São Paulo, Brazil. African ancestry was estimated through...

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Identifiers

PMID: 22064377
DOI: 10.1038/mp.2011.136
PMCID: PMC3526728

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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