Article
Genetic variation in serotonin transporter function affects human fear expression indexed by fear-potentiated startle.
Biological psychology - 1 Feb 2012
Klumpers Floris, Heitland Ivo, Oosting Ronald S, Kenemans J Leon, Baas Johanna M P
Abstract excerpt
The serotonin transporter (SERT) plays a crucial role in anxiety. Accordingly, variance in SERT functioning appears to constitute an important pathway to individual differences in anxiety. The current study tested the hypothesis that genetic variation in SERT function is associated with variability in the basic reflex physiology of defense. Healthy subjects (N=82) were presented with clearly instructed cues of...
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