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Article

Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.

Scientific reports - 14 Jan 2016

Pujadas G, Cervantes S, Tutusaus A, Ejarque M, Sanchez L, García A, Esteban Y, Fargas L, Alsina B, Hartmann C, Gomis R, Gasa R

Abstract excerpt

Transcriptional and signaling networks establish complex cross-regulatory interactions that drive cellular differentiation during development. Using microarrays we identified the gene encoding the ligand Wnt9a as a candidate target of Neurogenin3, a basic helix-loop-helix transcription factor that functions as a master regulator of pancreatic endocrine differentiation. Here we show that Wnt9a is expressed in the...

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Identifiers

PMID: 26771085
DOI: 10.1038/srep19223
PMCID: PMC4725895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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