Article
The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.
Development (Cambridge, England) - 1 Jul 2007
Nelson Shelley B, Schaffer Ashleigh E, Sander Maike
Abstract excerpt
Despite much progress in identifying transcriptional regulators that control the specification of the different pancreatic endocrine cell types, the spatiotemporal aspects of endocrine subtype specification have remained largely elusive. Here, we address the mechanism by which the transcription f...
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