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Article

The CDR3 region as the major driver of TREM-1 interaction with its ligands, an in silico characterization

1 Jan 2023

Abstract excerpt

The triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition receptor heavily investigated in infectious and non-infectious diseases. Because of its role in amplifying inflammation, TREM-1 has been explored as a diagnostic/prognostic biomarker. Further, as the receptor has been implicated in the pathophysiology of several diseases, therapies aiming at modulating its activity represent a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37122631
DOI: 10.1016/j.csbj.2023.04.008

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