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Article

Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq.

Nucleic acids research - 1 Feb 2012

Someya Tatsuhiko, Baba Seiki, Fujimoto Mai, Kawai Gota, Kumasaka Takashi, Nakamura Kouji

Abstract excerpt

Bacterial Hfq is a protein that plays an important role in the regulation of genes in cooperation with sRNAs. Escherichia coli Hfq (EcHfq) has two or more sites that bind RNA(s) including U-rich and/or the poly(A) tail of mRNA. However, functional and structural information about Bacillus subtilis Hfq (BsHfq) including the RNA sequences that specifically bind to it remain unknown. Here, we describe RNA aptamers...

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Identifiers

PMID: 22053080
DOI: 10.1093/nar/gkr892
PMCID: PMC3287200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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