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Article

MDSN: A Module Detection Method for Identifying High-Order Epistatic Interactions.

Genes - 18 Dec 2022

Sun Yan, Gu Yijun, Ren Qianqian, Li Yiting, Shang Junliang, Liu Jin-Xing, Guan Boxin

Abstract excerpt

Epistatic interactions are referred to as SNPs (single nucleotide polymorphisms) that affect disease development and trait expression nonlinearly, and hence identifying epistatic interactions plays a great role in explaining the pathogenesis and genetic heterogeneity of complex diseases. Many methods have been proposed for epistasis detection; nevertheless, they mainly focus on low-order epistatic interactions,...

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PMID: 36553670
DOI: 10.3390/genes13122403
PMCID: PMC9778340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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