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Article

GRIK4/KA1 protein expression in human brain and correlation with bipolar disorder risk variant status.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2012

Knight Helen M, Walker Robert, James Rachel, Porteous David J, Muir Walter J, Blackwood Douglas H R, Pickard Benjamin S

Abstract excerpt

The kainate class of ionotropic glutamate receptors is involved in the regulation of neuronal transmission and synaptic plasticity. Previously we reported that a deletion variant within the gene GRIK4, which encodes the KA1 kainate receptor subunit, was associated with a reduced risk of bipolar disorder and increased GRIK4 mRNA abundance. Using a high resolution immunohistochemistry technique, we characterized...

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Source

Identifiers

PMID: 22052594
DOI: 10.1002/ajmg.b.31248

Genes

GRIK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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GRIK4/KA1 protein expression in human brain and correlation with bipolar disorder risk variant status.PMID 22052594Read ↗

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