Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis.

doi:10.1186/1477-5751-10-14

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis.

Journal of negative results in biomedicine - 3 Nov 2011

Scarel-Caminaga Raquel M, Curtis Karen M C, Renzi Rivelto, Sogumo Patrícia M, Anovazzi Giovana, Viana Aline C, Kim Yeon J, Orrico Silvana R P, Cirelli Joni A

Abstract excerpt

BACKGROUND: The chemokine receptor 1 CXCR-1 (or IL8R-alpha) is a specific receptor for the interleukin 8 (IL-8), which is chemoattractant for neutrophils and has an important role in the inflammatory response. The polymorphism rs2234671 at position Ex2+860G>C of the CXCR1 gene causes a conservative amino acid substitution (S276T). This single nucleotide polymorphism (SNP) seemed to be functional as it was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Periodontitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CXCR1 gene

Share to CXCR2 gene

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin-8A

Source

Open in PubMed Open full text

Identifiers

PMID: 22051099
DOI: 10.1186/1477-5751-10-14
PMCID: PMC3229460

Genes

CXCR1
CXCR2

Variants

rs2234671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis.PMID 22051099Read ↗

Association of haplotypes in the IL8 gene with susceptibility to chronic periodontitis in a Brazilian population.Semantic proximity Read ↗

Association of haplotypes in the CXCR2 gene with periodontitis in a Brazilian population.Semantic proximity Read ↗

Lack of association of a functional polymorphism in the interleukin 8 gene with susceptibility to periodontitis.Semantic proximity Read ↗

Haplotypes in the interleukin 8 gene and their association with chronic periodontitis susceptibility.Semantic proximity Read ↗

Polymorphisms of pro-inflammatory cytokine genes and the risk for acute suppurative or chronic nonsuppurative apical periodontitis in a Colombian population.Semantic proximity Read ↗

Comprehensive analysis of interleukin-8 gene polymorphisms and periodontitis susceptibility.Semantic proximity Read ↗

Analysis of interleukin-8 gene variants reveals their relative importance as genetic susceptibility factors for chronic periodontitis in the Han population.Semantic proximity Read ↗

Interleukin-8 gene promoter polymorphism (rs4073) may contribute to chronic periodontitis.Semantic proximity Read ↗

The IL1A (-889) gene polymorphism is associated with chronic periodontal disease in a sample of Brazilian individuals.Semantic proximity Read ↗

Lack of association between IL-10 -1082G/A polymorphism and chronic periodontal disease in adults.Semantic proximity Read ↗

Interleukin-24, RANTES and CCR5 gene polymorphisms are not associated with chronic adult periodontitis.Semantic proximity Read ↗

Association of duffy blood group gene polymorphisms with IL8 gene in chronic periodontitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.