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Article

Analysis of interleukin-8 gene variants reveals their relative importance as genetic susceptibility factors for chronic periodontitis in the Han population.

PloS one - 1 Jan 2014

Zhang Nan, Xu Yuehong, Zhang Bo, Zhang Tianxiao, Yang Haojie, Zhang Bao, Feng Zufei, Zhong Dexing

Abstract excerpt

Interleukin (IL)-8, an important chemokine that regulates the inflammatory response, plays an important role in periodontitis. Previous studies indicate that certain IL-8 gene polymorphisms are associated with periodontitis susceptibility in some populations. However, the literature is somewhat contradictory, and not all IL-8 polymorphisms have been examined, particularly in Han Chinese individuals. The aim of...

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PMID: 25101955
DOI: 10.1371/journal.pone.0104436
PMCID: PMC4125212

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