Article
Association of haplotypes in the IL8 gene with susceptibility to chronic periodontitis in a Brazilian population.
Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010
Kim Yeon Jung, Viana Aline Cavalcante, Curtis Karen Maria C, Orrico Silvana Regina Perez, Cirelli Joni Augusto, Mendes-Junior Celso Teixeira, Scarel-Caminaga Raquel Mantuaneli
Abstract excerpt
BACKGROUND: Interleukin 8 (IL-8) is a chemokine related to the initiation and amplification of acute and chronic inflammatory processes. Polymorphisms in the IL8 gene have been associated with inflammatory diseases. We investigated whether the -845(T/C) and -738(T/A) single nucleotide polymorphis...
Topics
- Adult
- Brazil
- Chronic Disease
- Female
- Haplotypes
- Humans
- Interleukin-8
- Male
- Middle Aged
- Periodontitis
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide