Article
Association of haplotypes in the IL8 gene with susceptibility to chronic periodontitis in a Brazilian population.
Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010
Kim Yeon Jung, Viana Aline Cavalcante, Curtis Karen Maria C, Orrico Silvana Regina Perez, Cirelli Joni Augusto, Mendes-Junior Celso Teixeira, Scarel-Caminaga Raquel Mantuaneli
Abstract excerpt
BACKGROUND: Interleukin 8 (IL-8) is a chemokine related to the initiation and amplification of acute and chronic inflammatory processes. Polymorphisms in the IL8 gene have been associated with inflammatory diseases. We investigated whether the -845(T/C) and -738(T/A) single nucleotide polymorphisms (SNPs) in the IL8 gene, as well as the haplotypes they form together with the previously investigated -353(A/T), are...
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