Article
Lack of association of a functional polymorphism in the interleukin 8 gene with susceptibility to periodontitis.
DNA and cell biology - 1 Apr 2009
Kim Yeon J, Viana Aline C, Curtis Karen M C, Orrico Silvana R P, Cirelli Joni A, Scarel-Caminaga Raquel M
Abstract excerpt
The important inflammatory mediator interleukin-8 (IL-8) is responsible for the migration and activation of neutrophils. The IL8 gene contains a functional single-nucleotide polymorphism (SNP) (rs4073) in its promoter region that may influence the expression of IL-8, and which has been associated with inflammatory diseases. The purpose of this study was to investigate the association of the SNP (rs4073) in the...
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