Article
Association of duffy blood group gene polymorphisms with IL8 gene in chronic periodontitis.
PloS one - 1 Jan 2013
Sippert Emília Ângela, de Oliveira e Silva Cléverson, Visentainer Jeane Eliete Laguila, Sell Ana Maria
Abstract excerpt
The antigens of the Duffy blood group system (DARC) act as a receptor for the interleukin IL-8. IL-8 plays an important role in the pathogenesis of chronic periodontitis due to its chemotactic properties on neutrophils. The aim of this study was to investigate a possible association of Duffy blood group gene polymorphisms with the -353T>A, -845T>C and -738T>A SNPs of the IL8 gene in chronic periodontitis. One...
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