Article
The IL1A (-889) gene polymorphism is associated with chronic periodontal disease in a sample of Brazilian individuals.
Journal of periodontal research - 1 Feb 2007
Moreira P R, Costa J E, Gomez R S, Gollob K J, Dutra W O
Abstract excerpt
BACKGROUND AND OBJECTIVE: It has been proposed that genotypes reflective of polymorphisms in cytokine genes can predispose individuals to disease by enhancing inflammatory processes. The C/T polymorphism at position -889 of the IL1A gene influences interleukin-1alpha expression, with the T allele inducing higher expression. The aim of this study was to evaluate the association of the IL1A (-889) gene polymorphism...
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