Article
Haplotypes in the interleukin 8 gene and their association with chronic periodontitis susceptibility.
Biochemical genetics - 1 Jun 2011
Scarel-Caminaga Raquel M, Kim Yeon J, Viana Aline C, Curtis Karen M C, Corbi Sâmia C T, Sogumo Patrícia M, Orrico Silvana R P, Cirelli Joni A
Abstract excerpt
Interleukin-8 (IL-8), which is responsible for the migration and activation of neutrophils, is an important inflammatory mediator involved in the initiation and amplification of acute inflammatory reactions and chronic inflammatory processes. IL-8 plays an important role in periodontitis, an inflammatory disease characterized by the loss of connective tissue and alveolar bone. The aim of this study was to...
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