Article
Lack of association between IL-10 -1082G/A polymorphism and chronic periodontal disease in adults.
Genetics and molecular research : GMR - 22 Dec 2015
Hannum R, Godoy F R, da Cruz A S, Vieira T C, Minasi L B, de M E Silva D, da Silva C C, da Cruz A D
Abstract excerpt
Because of the complex interaction between periodontal pathogens and the host defense system, periodontitis is considered an inflammatory disorder of bacterial etiology that results in periodontal tissue damage. Genetic mechanisms may interfere with the gene expression of important inflammation mediators, modulating the immunologic response of an individual. In this study, we evaluated the single nucleotide...
Topics
- Adult
- Alleles
- Brazil
- Chronic Periodontitis
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-10
- Male