Distinctive Attributes of β-Lactam Target Proteins in <i>Acinetobacter baumannii</i> Relevant to Development of New Antibiotics

Abstract excerpt

Multi-drug-resistant forms of the Gram-negative pathogen Acinetobacter baumannii are an emerging threat to human health and further complicate the general problem of treating serious bacterial infections. Meeting this challenge requires an improved understanding of the relationships between the structures of major therapeutic targets in this organism and the activity levels exhibited against it by different...

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