Article
Structure of the extended-spectrum class C β-lactamase ADC-1 from<i>Acinetobacter baumannii</i>
21 Feb 2014
Abstract excerpt
ADC-type class C β-lactamases comprise a large group of enzymes that are encoded by genes located on the chromosome of Acinetobacter baumannii, a causative agent of serious bacterial infections. Overexpression of these enzymes renders A. baumannii resistant to various β-lactam antibiotics and thus severely compromises the ability to treat infections caused by this deadly pathogen. Here, the high-resolution...
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