Article
Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1.
Nature - 24 Oct 2002
Beisel Christian, Imhof Axel, Greene Jaime, Kremmer Elisabeth, Sauer Frank
Abstract excerpt
The establishment and maintenance of mitotic and meiotic stable (epigenetic) transcription patterns is fundamental for cell determination and function. Epigenetic regulation of transcription is mediated by epigenetic activators and repressors, and may require the establishment, 'spreading' and maintenance of epigenetic signals. Although these signals remain unclear, it has been proposed that chromatin structure...
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