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Article

Mutagenic evaluation of some triazino indoles using the Salmonella/mammalian microsome assay.

Mutagenesis - 1 Jul 1990

Lopez-de-Cerain A, García E, Gullón A, Recalde J I, Monge A

Abstract excerpt

The mutagenicity of ethyl 1,2,3-triazino[5,4-b]indole-4-carboxylate N(3)-oxide (D3) and 2-chloroethyl 1,2,3-triazino-[5,4-b]indole-4-carboxylate N(3)-oxide (D4), heads of series of new products with considerable platelet antiaggregating and hypotensive activity, and their precursors 2-ethoxy-carbonylmethyl-1-methylindole-3-carboxylic acid (A3) and 2-(2-chloroethoxycarbonylmethyl)-1-methylindole-3-carboxylic acid...

Topics

Animals
Indoles
Male
Mutagenicity Tests
Mutagens
Mutation
Platelet Aggregation Inhibitors
Rats
Rats, Inbred Strains
Regression Analysis
Salmonella typhimurium
Triazines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2204783
DOI: 10.1093/mutage/5.4.307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2204783-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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