Article
Mutagenic evaluation of some triazino indoles using the Salmonella/mammalian microsome assay.
Mutagenesis - 1 Jul 1990
Lopez-de-Cerain A, García E, Gullón A, Recalde J I, Monge A
Abstract excerpt
The mutagenicity of ethyl 1,2,3-triazino[5,4-b]indole-4-carboxylate N(3)-oxide (D3) and 2-chloroethyl 1,2,3-triazino-[5,4-b]indole-4-carboxylate N(3)-oxide (D4), heads of series of new products with considerable platelet antiaggregating and hypotensive activity, and their precursors 2-ethoxy-carbonylmethyl-1-methylindole-3-carboxylic acid (A3) and 2-(2-chloroethoxycarbonylmethyl)-1-methylindole-3-carboxylic acid...
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