Article
Mutagenic activity of p-toluenesulfonhydrazide.
Toxicology and industrial health - 1 Jan 2000
Blakey D H, Nestmann E R, Bayley J M, Maus K L, Douglas G R
Abstract excerpt
Toluenesulfonhydrazide (TSH) is a high volume production chemical for which there is relatively little toxicological data. In this study, the mutagenic activity of TSH was determined in the Salmonella/mammalian microsome assay and the in vitro chromosomal aberration assay using Chinese hamster ovary cells. TSH induced gene mutations both with and without metabolic activation in the Salmonella/mammalian microsome...
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