Article
Mutagenic activity of p-toluenesulfonhydrazide.
Toxicology and industrial health - 1 Jan 2000
Blakey D H, Nestmann E R, Bayley J M, Maus K L, Douglas G R
Abstract excerpt
Toluenesulfonhydrazide (TSH) is a high volume production chemical for which there is relatively little toxicological data. In this study, the mutagenic activity of TSH was determined in the Salmonella/mammalian microsome assay and the in vitro chromosomal aberration assay using Chinese hamster ov...
Topics
- Animals
- Biotransformation
- CHO Cells
- Cells, Cultured
- Chromosome Aberrations
- Computer Simulation
- Cricetinae
- Microsomes
- Mutagenicity Tests
- Mutagens
- Mutation
- Rats
- Rats, Sprague-Dawley
- Salmonella
- Tosyl Compounds