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Article

Mutagenicity of 2 anti-chagasic drugs and their metabolic deactivation.

Mutation research - 1 Jan 2000

Nagel R, Nepomnaschy I

Abstract excerpt

2 anti-chagasic drugs, nifurtimox and benznidazole, were assayed in the Salmonella/mammalian microsome test. These drugs were most active in strain TA100. Under certain experimental conditions, addition of rat-liver S9 mix led to a decrease in the number of his+ revertants induced by the drugs.

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Source

Identifiers

PMID: 6406881
DOI: 10.1016/0165-1218(83)90124-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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