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Article

Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia.

PLoS genetics - 1 Oct 2011

An Ping, Li Rongling, Wang Ji Ming, Yoshimura Teizo, Takahashi Munehisa, Samudralal Ram, O'Brien Stephen J, Phair John, Goedert James J, Kirk Gregory D, Troyer Jennifer L, Sezgin Efe, Buchbinder Susan P, Donfield Sharyne, Nelson George W, Winkler Cheryl A

Abstract excerpt

Chromosome 3p21-22 harbors two clusters of chemokine receptor genes, several of which serve as major or minor coreceptors of HIV-1. Although the genetic association of CCR5 and CCR2 variants with HIV-1 pathogenesis is well known, the role of variation in other nearby chemokine receptor genes remain unresolved. We genotyped exonic single nucleotide polymorphisms (SNPs) in chemokine receptor genes: CCR3, CCRL2, and...

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Share to Acquired Immunodeficiency Syndrome
Share to Chromosomes, Human, Pair 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HEK293 Cells

Share to Pneumonia, Pneumocystis

Share to Receptors, Chemokine

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Source

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Identifiers

PMID: 22046140
DOI: 10.1371/journal.pgen.1002328
PMCID: PMC3203199

Genes

CCRL2
CCR2
CCR3
CCR5
CCR8
CXCR6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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