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Article

Receptor Tyrosine Kinases as Therapeutic Targets the Model of the MET Oncogene

1 Mar 2001

Abstract excerpt

Control of cell growth and differentiation occurs via extracellular signals known as growth factors. Growth factors are high affinity ligands for transmembrane receptors belonging to the family of receptor tyrosine kinases (RTKs). A number of genetic evidences have implicated RTKs in human diseases including developmental disorders and cancer. For instance, germline missense mutations involving the Ret receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11465538
DOI: 10.2174/1389450013348920

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