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Receptor Tyrosine Kinase-Targeted Cancer Therapy

6 Nov 2018

Abstract excerpt

In the past two decades, several molecular targeted inhibitors have been developed and evaluated clinically to improve the survival of patients with cancer. Molecular targeted inhibitors inhibit the activities of pathogenic tyrosine kinases. Particularly, aberrant receptor tyrosine kinase (RTK) activation is a potential therapeutic target. An increased understanding of genetics, cellular biology and structural...

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PMID: 30404198
DOI: 10.3390/ijms19113491

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