Article
The relationship between three heat shock protein 70 gene polymorphisms and susceptibility to lung cancer.
Clinical chemistry and laboratory medicine - 1 Nov 2010
Wang Yuzhen, Zhou Fang, Wu Yiming, Xu Dong, Li Weihui, Liang Shoupei
Abstract excerpt
BACKGROUND: Heat shock protein 70 (Hsp70) has been shown to act as a chaperone and be associated with a variety of tumors. We investigated HSP70-1 G+190C, HSP70-2 A+1267G, and HSP70-hom T+2437C polymorphisms to assess whether genetic variation in HSP70 plays a role in the occurrence and development of lung cancer. METHODS: A case-control study was conducted using 159 patients with lung cancer and 202 control...
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