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Article

Ku regulates signaling to DNA damage response pathways through the Ku70 von Willebrand A domain.

Molecular and cellular biology - 1 Jan 2012

Fell Victoria L, Schild-Poulter Caroline

Abstract excerpt

The Ku heterodimer (Ku70/Ku80) is a main component of the nonhomologous end-joining (NHEJ) pathway that repairs DNA double-strand breaks (DSBs). Ku binds the broken DNA end and recruits other proteins to facilitate the processing and ligation of the broken end. While Ku interacts with many proteins involved in DNA damage/repair-related functions, few interactions have been mapped to the N-terminal von Willebrand...

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Source

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Identifiers

PMID: 22037767
DOI: 10.1128/MCB.05661-11
PMCID: PMC3255697

Genes

ATF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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