Article
Differential modulation of excitatory and inhibitory striatal synaptic transmission by histamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 Oct 2011
Ellender Tommas J, Huerta-Ocampo Icnelia, Deisseroth Karl, Capogna Marco, Bolam J Paul
Abstract excerpt
Information processing in the striatum is critical for basal ganglia function and strongly influenced by neuromodulators (e.g., dopamine). The striatum also receives modulatory afferents from the histaminergic neurons in the hypothalamus which exhibit a distinct diurnal rhythm with high activity during wakefulness, and little or no activity during sleep. In view of the fact that the striatum also expresses a high...
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