Sexual dimorphism in histamine regulation of striatal dopamine

Abstract excerpt

Dopamine modulation of the basal ganglia differs in males and females and is implicated in numerous neuropsychiatric conditions, including some, like Tourette Syndrome (TS) and attention deficit hyperactivity disorder (ADHD), that have marked sex differences in prevalence. Genetic studies in TS and subsequent work in animals suggest that a loss of histamine may contribute to dysregulation of dopamine. Motivated by...

Topics

Open a Topic to create a Post that cites this publication.

• Amphetamine
• Attention Deficit Hyperactivity Disorder
• Dopamine Agonists
• Dopamine Antagonists
• Exploratory Behavior
• Mast cells and histamine
• Obsessive-Compulsive Spectrum Disorders
• Tourette Syndrome

Identifiers and source

Literature Corpus work

a752816a-e0e6-5c05-8625-39232d9fd5b4

DOI

10.1101/2024.05.20.595049