Article

Mechanisms underlying serotonergic excitation of callosal projection neurons

2017-10-03

Abstract excerpt

Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT 2A (2A) receptors coupled to G q subtype G-protein alpha subunits. Gq-mediated excitatory responses have been attributed primarily to suppression of potassium conductances, including those mediated by K V 7 potassium channels (i.e., the M-current), or activation of nonspecific cation conductances tha...

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Literature Corpus work: 1be4dbbd-08de-5d37-a337-307c3b631deb
DOI: 10.1101/197624

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