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FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development

27 Oct 2011

Abstract excerpt

Recent studies indicate that nephron progenitor cells of the embryonic kidney are arranged in a series of compartments of an increasing state of differentiation. The earliest progenitor compartment, distinguished by expression of CITED1, possesses greater capacity for renewal and differentiation than later compartments. Signaling events governing progression of nephron progenitor cells through stages of...

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PMID: 22031548
DOI: 10.1242/dev.065995

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