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Article

FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.

Development (Cambridge, England) - 1 Sept 2005

Grieshammer Uta, Cebrián Cristina, Ilagan Roger, Meyers Erik, Herzlinger Doris, Martin Gail R

Abstract excerpt

During kidney morphogenesis, the formation of nephrons begins when mesenchymal nephron progenitor cells aggregate and transform into epithelial vesicles that elongate and assume an S-shape. Cells in different regions of the S-shaped body subsequently differentiate into the morphologically and fun...

Read the complete abstract on PubMed

Topics

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Share to Cell Survival
Share to Fibroblast Growth Factor 8
Share to Fibroblast Growth Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Mesoderm

Share to Mice, Transgenic

Share to Nephrons

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Source

Identifiers

PMID: 16049112
DOI: 10.1242/dev.01944

Genes

FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16049112-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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