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Article

FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.

Development (Cambridge, England) - 1 Sept 2005

Grieshammer Uta, Cebrián Cristina, Ilagan Roger, Meyers Erik, Herzlinger Doris, Martin Gail R

Abstract excerpt

During kidney morphogenesis, the formation of nephrons begins when mesenchymal nephron progenitor cells aggregate and transform into epithelial vesicles that elongate and assume an S-shape. Cells in different regions of the S-shaped body subsequently differentiate into the morphologically and functionally distinct segments of the mature nephron. Here, we have used an allelic series of mutations to determine the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Developmental

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Source

Identifiers

PMID: 16049112
DOI: 10.1242/dev.01944

Genes

FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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