Article
Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women.
Psychiatric genetics - 1 Dec 2011
Scheid Jeanette M, Holzman Claudia B, Jones Nicole, Friderici Karen H, Jernigan Katherine A, Symonds Laura L, Sikorskii Alla, Fisher Rachel
Abstract excerpt
OBJECTIVE: In earlier analyses of nonHispanic White women we found a stronger relation between abuse history and midpregnancy elevated depressive symptoms in women with the serotonin transporter (5-HTTLPR) S/S genotype. Here, we focus on African-American women (N=698). Our inquiry is motivated by racial differences in depression diagnosis/treatment, stressors, and frequency of major 5-HTTLPR alleles (S, LA, LG)....
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